May 23, 2024 Webinar
The webinar explored the GrimAge epigenetic biological age test and its 10 Systems Aging Risk Factors. Participants learned how this test helps individuals track biological age and gain insights into personalized aging profiles while understanding mechanisms affecting longevity.
Speakers & Topics
Mark Koester (Head of Product, Longevity Biohacker)
- Shared personal GrimAge results demonstrating a 6.1-year reduction in biological age
- Discussed lifestyle interventions: exercise, sleep optimization, stress management, plant-based diet, and intermittent fasting
Bobby Brooke (Executive Director, Epigenetic Expert)
- Explained GrimAge mechanisms and the 10 risk factors
- Reviewed recent longevity research papers and treatment developments
The 10 GrimAge Risk Factors
- Cystatin C - Kidney function/renal aging
- GDF-15 - Muscle function/cellular senescence
- HbA1c - Metabolic/glycemic health
- CRP - Systemic inflammation
- PACKYRS - Lung function/smoking exposure
- PAI-1 - Vascular function/blood clotting
- TIMP-1 - Extracellular matrix/tissue health
- Leptin - Immune system modulation
- ADM - Vascular function/cellular aging
- B2M - Brain inflammation/neuroinflammation
Notable Treatment Research Reviewed
- Exosome/extracellular vesicle therapies for mitochondrial function
- Umbilical cord-derived stem cells for frailty
- Metabolite reprogramming for muscle regeneration
- Immune system interventions (myeloid-biased stem cell depletion)
Key Takeaway
Understanding your unique aging drivers is key to living a longer, healthier life through personalized, data-driven interventions.
